Cape Girardeau has 6 dispensaries licensed by the Missouri Division of Cannabis Regulation (DCR). If you are 21 or older and have a valid photo ID, you can buy here whether you live in Missouri, Illinois or anywhere else. The 6 stores also take care of registered medical patients. Cape has more dispensaries than any other city in Southeast Missouri.
Cape Girardeau is the shopping hub for a wide stretch of the Mississippi valley, and its stores reflect that: they are big, busy and well reviewed, with ratings between 4.7 and 4.9 stars. Two roads do nearly all the work, Kingshighway and Broadway, so most shoppers can reach a store within a few minutes of I-55 or downtown.
All 6 Licensed Dispensaries in Cape Girardeau, MO
Three of the stores are in the 63701 ZIP code, covering downtown and central Cape, and three are in 63703 on the south side. State data in our Missouri directory shows one of the state's few microbusiness dispensaries, the smaller license created by the 2022 amendment, among Cape Girardeau's stores.
Kingshighway: the city's main north-south commercial road has three stores. Codes Cannabis is on North Kingshighway, while Proper Cannabis Cape Girardeau and High Profile are on South Kingshighway.
Broadway: Greenlight Dispensary at 1001 Broadway and Good Day Farm at 1330 Broadway are a few blocks apart on the road that runs west from the riverfront. South Plaza Way: Grass Roots Dispensary is in the 63703 shopping area on the south side.
Best Cape Girardeau Dispensaries for Every Need
From public Google ratings and hours, checked October 2026:
- Highest rated: Good Day Farm (4.9 stars, about 1,500 reviews) and Grass Roots (4.9 stars, about 340).
- Most reviewed: High Profile, with about 1,900 reviews.
- Opens first: Greenlight, High Profile and Proper Cannabis all open at 8 a.m.
- Closes last: five stores stay open until 10 p.m.
- Closes earliest: Grass Roots, at 8 p.m.
- Patients: all 6 stores serve Missouri medical card holders.
Visiting a Dispensary in Cape Girardeau: ID, Payment and Hours
An Illinois, Kentucky or Tennessee driver's license is just as good as a Missouri one, provided it is valid and you are 21. Bring cash or debit; not every store runs credit cards. Stores here open at 8 or 9 a.m., and each sets its own closing time.
Cape Girardeau and Missouri Cannabis Laws: Purchase Limits, Public Use and Driving
The law lets an adult buy 3 ounces of dried marijuana, or the equivalent in other forms, per transaction, and hold up to 3 ounces. The riverfront, Capaha Park and other public spaces are off limits for smoking, with a civil fine of up to $100. Driving while impaired is illegal, and so is driving cannabis over the Bill Emerson Memorial Bridge into Illinois: even though Illinois has a legal market, crossing a state line with cannabis breaks the law. Read our Missouri marijuana law guide for possession and grow rules, or compare neighboring states' cannabis laws.
Cannabis Taxes in Cape Girardeau
City voters approved a 3% tax on adult-use marijuana in April 2023, and the Missouri Department of Revenue's rate table for October to December 2026 lists a 3% local adult-use rate for Cape Girardeau. On top of that come Missouri's 6% state tax and the regular sales tax, which is 8.475% at the city's base rate and higher in districts such as the Town Plaza and downtown improvement districts. Medical purchases are taxed at 4%.
Medical Marijuana in Cape Girardeau
Missouri patients shop at any of the six stores, pay the lower 4% tax and may buy up to 6 ounces every 30 days. Missouri's card is also the only way to buy here under 21, and anyone under 18 needs a parent or guardian to hold it.
Dispensaries Near Cape Girardeau
- Dispensaries in Sikeston: 2 stores about 30 miles south on I-55.
- Dispensaries in Dexter: 1 store to the southwest.
- Dispensaries in Poplar Bluff: 2 stores farther southwest on US 60.
- Dispensaries in Kennett: 1 store in the Bootheel.
Search all Missouri cities on our Missouri dispensary directory.
Cape Girardeau Dispensary FAQ
Is weed legal in Cape Girardeau?
Yes. Adults 21 and over can buy cannabis from Cape Girardeau's licensed dispensaries, though not use it in public.
How many dispensaries are in Cape Girardeau?
6, the most of any Southeast Missouri city. Sikeston and Poplar Bluff, the next biggest, have two each.
Can people from Illinois buy weed in Cape Girardeau?
Yes, with a valid ID showing they are 21 or older. They cannot legally carry it back across the river.
What time do dispensaries close in Cape Girardeau?
10 p.m. at five of the six stores. Grass Roots on South Plaza Way closes at 8 p.m.
Do Cape Girardeau dispensaries take cards?
Debit usually, credit sometimes. Cash works everywhere.
How much can I buy in Cape Girardeau?
3 ounces of flower or its equivalent per transaction, the Missouri adult limit.
Where can I smoke weed in Cape Girardeau?
Private property with permission. Smoking in a public place such as the riverfront can bring a fine of up to $100.
Can I get weed delivered in Cape Girardeau?
Missouri permits dispensary delivery, but each store decides whether to offer it. Ask the store directly.
What is the best dispensary in Cape Girardeau?
Good Day Farm and Grass Roots lead with 4.9 stars, and High Profile has the most reviews. See the ratings list above.
Which street in Cape Girardeau has the most dispensaries?
Kingshighway, with three stores. Broadway has two.
Does your dispensary need more visibility? Cannabis shoppers use The Weed Street Journal to compare stores, read strain guides and check the law before they buy. Advertise with us · Spotted a wrong address, phone number or hours? Tell us and we will fix it free.
How we build this list: Our source for store names, addresses and license numbers is the Missouri Division of Cannabis Regulation's dispensary license list; ratings, review counts and hours are pulled from public Google Maps data. The page is updated monthly, and unlicensed stores are removed.