O'Fallon has 4 dispensaries licensed by the Missouri Division of Cannabis Regulation (DCR). To buy, you must be 21 or older with a valid government-issued photo ID; Missouri residency is not required. All 4 stores are also open to registered medical patients. This page covers O'Fallon, Missouri, in St. Charles County, not O'Fallon, Illinois, across the Mississippi in the Metro East.
O'Fallon is a big St. Charles County suburb with a compact dispensary scene built around the highway: two of the four stores share West Terra Lane, and the others sit on Bryan Road and Highway N. With one store open around the clock, it is an easy late-night stop for anyone on I-70 or Highway 364.
All 4 Licensed Dispensaries in O'Fallon, MO
Three stores are in the 63366 ZIP code in the center and north of the city, and one is in 63304 on the south side along Highway N.
West Terra Lane and Bryan Road (63366): Terrabis at 1172 West Terra Lane and Missouri Wild Alchemy at 2173 West Terra Lane are on the same road. Nature Med Dispensary is on Bryan Road. Highway N (63304): Key Cannabis Dispensary is the store for south O'Fallon.
Best O'Fallon Dispensaries for Every Need
Ranked with public Google ratings and hours, checked October 2026:
- Highest rated: Missouri Wild Alchemy, 4.8 stars from about 440 reviews.
- Most reviewed: Nature Med, 4.7 stars from about 1,400 reviews.
- Open all night: Terrabis lists 24-hour hours.
- Earliest daytime opening: Nature Med and Key Cannabis open at 8 a.m.
- Latest daytime close: Nature Med, at 10 p.m.; Key Cannabis closes at 9:45 and Missouri Wild Alchemy at 9.
Visiting a Dispensary in O'Fallon: ID, Payment and Hours
Show a current license, state ID or passport with your birth date. Plan on cash or a debit card, as credit card policies differ by store. If you are driving over from Illinois, remember that a Missouri store will happily sell to you, but the drive home with your purchase is the illegal part.
O'Fallon and Missouri Cannabis Laws: Purchase Limits, Public Use and Driving
In one transaction an adult can buy up to 3 ounces of dried marijuana or the equivalent, and that is also the most an adult may possess. Lighting up in Fort Zumwalt Park, at a ballfield or on any other public property can mean a fine of up to $100. Landlords and other property owners may ban it on property they control. Driving while impaired is illegal, and crossing into Illinois with cannabis is illegal even though Illinois has its own dispensaries. Our Missouri marijuana law guide has more.
Cannabis Taxes in O'Fallon
The City of O'Fallon's finance department lists an adult-use marijuana local sales tax of 3.0%, and the Missouri Department of Revenue's October to December 2026 rate table shows the same 3% for the city. Shoppers also pay Missouri's 6% adult-use tax plus regular sales tax, which is 7.95% at the city's base rate and higher in some community improvement districts. Medical purchases carry a 4% tax instead.
Medical Marijuana in O'Fallon
A Missouri patient card brings a 4% tax rate, a purchase allowance of 6 ounces every 30 days and access for patients under 21. Every O'Fallon store serves card holders.
Dispensaries Near O'Fallon
- Dispensaries in St. Peters: 6 stores next door to the east.
- Dispensaries in Cottleville: 1 store just to the southeast.
- Dispensaries in St. Charles: 2 stores toward the Missouri River.
- Dispensaries in Warrenton: 1 store west on I-70.
- Dispensaries in Chesterfield: 2 stores across the Missouri River in West County.
Check other towns on our Missouri directory of dispensaries.
O'Fallon Dispensary FAQ
Is weed legal in O'Fallon, MO?
Yes. Adults 21 and older can buy at any licensed O'Fallon dispensary, but public use is banned.
How many dispensaries are in O'Fallon?
4. St. Peters, right next door, has a few more.
Is O'Fallon, Missouri the same as O'Fallon, Illinois?
No. They are separate cities in different states, on opposite sides of St. Louis. This page lists only the Missouri stores.
Can tourists buy weed in O'Fallon?
Yes. Any adult 21 or older with valid photo ID can buy, with no residency requirement.
Is there a 24-hour dispensary in O'Fallon?
Terrabis on West Terra Lane lists itself as open 24 hours on Google.
Do O'Fallon dispensaries take credit cards?
Policies differ. Cash and debit work almost everywhere.
How much weed can I buy in O'Fallon?
Up to 3 ounces of flower or its equivalent in a single transaction.
Where can I legally smoke in O'Fallon?
On private property with the owner's consent, never in a park, a parking lot or a car.
Can I get weed delivered in O'Fallon?
Missouri allows dispensary delivery. Whether you can get it depends on the store and its delivery zone.
What is the best dispensary in O'Fallon?
Missouri Wild Alchemy has the top rating at 4.8 stars, and Nature Med has the most reviews. See the ratings list above.
Does your dispensary need more visibility? Cannabis shoppers use The Weed Street Journal to compare stores, read strain guides and check the law before they buy. Advertise with us · Spotted a wrong address, phone number or hours? Tell us and we will fix it free.
How we build this list: Store details, including name, address and license number, follow the Missouri Division of Cannabis Regulation's licensed dispensary data, while ratings, review counts and hours follow public Google Maps listings. We update monthly and remove any store whose license is no longer active.