Guptilla is an indica-dominant cannabis strain bred by Colorado Seed Inc. from Gorilla Glue #4 and Gupta Kush, known for a pungent, floral and earthy nose and a heavy, relaxing body effect. The breeder lists THC at 25% to 27%, which puts it among the stronger strains on the market. Reviewers describe a fast head rush that settles into deep physical calm, so most people save it for the evening.

Guptilla Strain at a Glance

Type Indica-dominant hybrid (about 60–70% indica)
Lineage Gorilla Glue #4 × Gupta Kush
Breeder / origin Colorado Seed Inc.
THC 25–27% (breeder figure; some listings go higher) (typical lab range)
CBD Not reported
Aroma and flavor pungent, floral, earthy, citrus, pine, grape, lemon, pepper, kush
Reported effects relaxed, happy, euphoric, heavy body, sleepy
Best for evening use, experienced consumers, unwinding after work
Flowering time 8–9 weeks (Weedmaps: 56–63 days)

Where Guptilla Comes From

Guptilla comes from Colorado Seed Inc., a Colorado seed company that sells it as regular (non-feminized) seeds. The breeder’s own listing gives the cross as Gorilla Glue #4 and Gupta Kush, and Leafly, Weedmaps and AllBud all repeat that same pairing, so the lineage is about as settled as it gets for a small-batch strain. The name is a simple blend of the two parents: Gupta plus the back half of Gorilla.

According to Colorado Seed Inc., the goal was to keep what growers like about Gorilla Glue #4 while pushing THC higher and building bigger, thicker buds. The company compares the bud density to OG Kush and rates the plant easy to grow, with strong upright growth and even spacing between nodes.

Guptilla has stayed a fairly rare strain. AllBud calls it super rare, and a Leafly reviewer noted it is hard to find outside Colorado. It mostly circulates through seed sales and the occasional craft grower, rather than as a large brand release. We found no documented awards and no named offspring.

Guptilla Effects: What It Feels Like

Reviewers on Leafly, AllBud and Weedmaps tell a consistent story. The high comes on quickly and starts in the head, with a burst of happy, euphoric and sometimes giggly energy. Over the next stretch it moves down into the body and becomes a heavy, sedating weight. Leafly rates the overall profile as mostly calming, and its top user tags are relaxed, happy and aroused. AllBud lists body high, happy and sleepy, and its description says the come-down often leads into long, heavy sleep. Colorado Seed Inc. describes it as an anchored, focused high suited to unwinding after work.

There are a few outliers. One Leafly reviewer used it before the gym and felt energetic, and another found it clear and cerebral at first with no anxiety. Most people, though, describe a couch-friendly strain. AllBud warns that it can easily overwhelm inexperienced users, and reviewers advise against using it in the morning. If your tolerance is low, take one small hit and wait a good 15 minutes before deciding on more.

Guptilla Terpenes, Aroma and Flavor

The breeder sums up the smell as pungent, floral and earthy, and the databases fill in the details. Reviewers mention citrus, pine, berry and a gassy edge, and AllBud lists lemon, pine and earthy kush among its aromas. One AllBud reviewer compared the smell to burnt rubber, a note that fits the Gorilla Glue side of the family.

On the palate, Leafly’s flavor tags are pepper, grape and blue cheese, while AllBud describes sweet lemon and grape with fresh kush and pine on the finish. Weedmaps users describe tart citrus, sweet grape, pine and earth. No source publishes a terpene lab profile for Guptilla, so we do not name dominant terpenes here. The buds are described as lumpy, bright green nugs with thin yellow-green hairs and a heavy coat of trichomes.

Side Effects and How to Use Guptilla

Leafly users list dry mouth, dry eyes and dizziness as the main downsides. At higher doses several reviewers describe couch-lock, which is the point for some people and a problem for anyone who still has things to do. With THC in the mid-20s or higher, overdoing it is the bigger risk, so keep doses small, drink water, and do not drive.

If you are new to Guptilla, start with one small inhalation or 2.5 mg in an edible and wait before taking more; see our dosing guide.

Do People Use Guptilla for Medical Reasons?

On Leafly, the people who reviewed Guptilla most often say they reached for it for stress (29%), anxiety (29%) and pain (26%). AllBud’s listing adds insomnia and muscle spasms. These are self-reports from a small number of reviewers, not evidence that the strain helps any condition.

These are user reports, not clinical findings. For what research actually supports, see our cannabis health and research section, and talk to your doctor before using cannabis for a health condition.

Growing Guptilla

  • Difficulty: Easy
  • Flowering: 8–9 weeks (Weedmaps: 56–63 days)
  • Yield: High, per the breeder
  • Height: Average
  • Environment: Indoors or outdoors; outdoor harvest around the end of September

Colorado Seed Inc. rates Guptilla easy to grow and calls it a prolific producer. The breeder recommends a longer vegetative period and multiple toppings for the best yields, and Weedmaps notes the same, saying it can deliver large harvests of dense buds when topped and vegged longer. Plants grow to average height with long, narrow leaves. Indoors it finishes in roughly eight to nine weeks of flowering, and outdoor plants are ready around the end of September. The buds are dense, so in a wet Pacific Northwest autumn give them strong airflow and watch for bud rot near harvest.

Home-grow rules depend on the state: adults can grow at home in states such as California (six plants per residence), Michigan (12 per residence) and Oregon (four per household), while Washington and Illinois allow home growing only for registered medical patients. Check your state in our cannabis laws by state guide before you plant anything.

Strains Like Guptilla

Browse more indica strains, the full strain directory, or our guide to cannabis strains.

More Indica Strains to Explore

Gush Mints · Gushers · Hades Haze · Gumbo · Grimmdica · Grape Zkittlez · All indica strains

Where to Buy Guptilla

Dispensary menus change every week, and Guptilla may be sold under its own name, as a cross or as a pre-roll or vape. The fastest way to find it is to check store menus online before you go. In Chicago, browse Chicago dispensaries and check the menus at stores like Dr Greenthumb’s Chicago and Verilife – Chicago River North. In Detroit, browse Detroit dispensaries and check the menus at stores like Green Acres Eight Mile and Dank Garden. You can also browse licensed dispensaries in every state we cover. Adults 21 and older can buy with a valid photo ID; see cannabis laws by state for purchase limits.

Guptilla FAQ

Is Guptilla indica or sativa?

Guptilla is an indica-dominant hybrid. Colorado Seed Inc. lists it at about 60% indica, and AllBud puts it closer to 70%.

What is Guptilla a cross of?

Guptilla is a cross of Gorilla Glue #4 and Gupta Kush, according to the breeder and every major strain database.

Who bred Guptilla?

Colorado Seed Inc. bred Guptilla and sells it as regular seeds.

How strong is Guptilla?

The breeder lists 25% to 27% THC, and reviewers have reported tested samples at 25.4% and 27%. AllBud lists an average closer to 29%, so treat it as a very strong strain.

What does Guptilla taste like?

Reviewers describe sweet grape and lemon with pepper, pine and earthy kush, over a pungent, floral smell.

Is Guptilla good for sleep?

Many reviewers say yes. The high starts in the head but turns heavy and sedating, and AllBud’s description says it often ends in long, deep sleep.

For adults 21+ in legal states. Strain information reflects breeder descriptions, lab data and user reports; effects vary by person and batch. Not medical advice.