Agent Orange is a sativa-leaning hybrid cannabis strain bred by MzJill Genetics from Orange Velvet and Jack the Ripper, known for a fresh-cut citrus aroma and an uplifting daytime high. Leafly lists its terpene lead as myrcene, followed by terpinolene. Reported THC runs from about 17% on Leafly to 25% on AllBud.
Agent Orange Strain at a Glance
| Type | Sativa-leaning hybrid |
|---|---|
| Also known as | Agent O |
| Lineage | Orange Velvet × Jack the Ripper |
| Breeder / origin | MzJill Genetics |
| THC | 17–25% (typical lab range) |
| CBD | Under 1% |
| Dominant terpenes | Myrcene, Terpinolene, Beta-caryophyllene |
| Aroma and flavor | fresh-cut citrus, orange, sweet, citrus |
| Reported effects | uplifted, happy, focused, creative |
| Best for | daytime use, creative tasks, social settings |
Where Agent Orange Comes From
Leafly credits Agent Orange to MzJill Genetics and lists Orange Velvet and Jack the Ripper as the parents. AllBud gives a different recipe, Orange Skunk crossed with Jack’s Cleaner and Space Queen, so the lineage is disputed. The Leafly version matches the breeder’s attribution and is the one used here.
The name refers to the Vietnam-era herbicide, which some consumers dislike. The strain has regional popularity in Michigan and the Pacific Northwest according to AllBud, and Leafly lists Orange Z and Orange Fanta as its offspring.
Agent Orange Effects: What It Feels Like
Users describe Agent Orange as uplifted, happy and focused, and Leafly classes it as mostly energizing. AllBud adds creative, giggly and sociable, and says the peak fades after about 30 minutes, which suits daytime activity.
The racier end shows up for some: anxiety is among the reported negatives. A modest dose keeps it bright and talkative instead of jittery.
Agent Orange Terpenes, Aroma and Flavor
The citrus is the point. The aroma is described as fresh-cut orange, with sweet flavors on the inhale. Buds carry deep maroon and purple pigments, which stand out against the orange hairs.
Leafly lists myrcene (earthy, herbal) first, then terpinolene (fruity) and caryophyllene (peppery).
- Myrcene: earthy, musky and herbal, also found in mango and hops
- Terpinolene: fruity, piney and herbal, common in classic sativas
- Beta-caryophyllene: peppery and spicy, also found in black pepper and cloves
Terpene levels vary from grower to grower and batch to batch, so check the lab label on the package. Learn more in our guide to cannabis terpenes.
Side Effects and How to Use Agent Orange
Dry mouth and dry eyes are common, and some users report anxiety, especially at higher doses. AllBud describes few adverse effects overall. Start low if you are sensitive to sativa-style strains.
How strong Agent Orange feels depends on the batch, your tolerance and how you consume it. Start low, go slow, and read our guide to dosing cannabis.
Do People Use Agent Orange for Medical Reasons?
Leafly readers say they use it for stress (36%), anxiety (30%) and depression (28%). AllBud lists a wider set of things users reach for, including fatigue and headaches. These are self-reports, not medical claims.
These are user reports, not clinical findings. For what research actually supports, see our cannabis health and research section, and talk to your doctor before using cannabis for a health condition.
Strains Like Agent Orange
- Tangie: another bright orange-citrus daytime strain
- Mimosa: citrus-forward and uplifting
- Super Lemon Haze: energizing citrus sativa
- Lemon Haze: zesty, clear-headed lift
- Zkittlez: fruity profile and a relative of its Orange Z offspring
Browse more sativa strains, the full strain directory, or our guide to cannabis strains.
More Sativa Strains to Explore
AK-47 · Alaskan Thunder Fuck · Amnesia Haze · Afghan Haze · ACDC · Acapulco Gold · All sativa strains
Where to Buy Agent Orange
Dispensary menus change every week, and Agent Orange may be sold under its own name, as a cross or as a pre-roll or vape. The fastest way to find it is to check store menus online before you go. In Lansing, browse Lansing dispensaries and check the menus at stores like Lake Life Farms and Canna Plug. In Chicago, browse Chicago dispensaries and check the menus at stores like Green Rose – Chicago and BLOC Dispensary Kedzie. You can also browse licensed dispensaries in every state we cover. Adults 21 and older can buy with a valid photo ID; see cannabis laws by state for purchase limits.
Agent Orange FAQ
Is Agent Orange indica or sativa?
Agent Orange leans sativa. Leafly calls its effects mostly energizing and AllBud lists it at about 75% sativa.
Who bred Agent Orange?
MzJill Genetics, according to Leafly.
What is Agent Orange a cross of?
Leafly lists Orange Velvet and Jack the Ripper. AllBud gives a different recipe, so the lineage is disputed.
How strong is Agent Orange?
Leafly shows about 17% THC and AllBud about 25%, so batches vary.
What does Agent Orange taste like?
Sweet orange and citrus, with earthy herbal notes underneath.
For adults 21+ in legal states. Strain information reflects breeder descriptions, lab data and user reports; effects vary by person and batch. Not medical advice.
