Medford
Oregon
97504
United States
Substance Crater Lake Hwy at a glance
| Known for | A large showroom with a wide flower range, including older strains reviewers could not find elsewhere, and clear price breaks |
|---|---|
| Hours | 8 a.m.–9 p.m. Monday to Friday; 9 a.m.–9 p.m. Saturday and Sunday |
| Location | 3425 Crater Lake Hwy, about 1.1 miles from Rogue Valley International-Medford Airport |
| Ownership | Substance, an Oregon chain with stores in Bend, Springfield, Lakeview and more |
| Google rating | 5 out of 5 (43 reviews) |
| License | OLCC #050-10174595F3A · medically endorsed |
Details verified October 13, 2026 against state license records and the store’s Google Business Profile.
- 5.0★ from 43 Google reviews
- Large, easy-to-browse showroom
- Hard-to-find strains, per reviewers
- Online ordering
- Medical retailer endorsement
- 1.1 mi from the Medford airport
About Substance Crater Lake Hwy
Substance Crater Lake Hwy is the closest dispensary to Rogue Valley International-Medford Airport, about 1.1 miles away, and 1.7 miles from Rogue Valley Mall. It is one of two Substance stores in Medford.
Reviewers describe a big sales floor where products are easy to see, a wide selection that includes older strains they could not find elsewhere, and clear price breaks on flower. One reviewer praises an online order, and another notes easy parking.
Substance holds OLCC medical-retailer and home-delivery endorsements. Google lists a wheelchair-accessible entrance and parking lot. Google also tags the store LGBTQ+ friendly.
Substance Crater Lake Hwy Hours
| Day | Open |
|---|---|
| Monday | 8 a.m.–9 p.m. |
| Tuesday | 8 a.m.–9 p.m. |
| Wednesday | 8 a.m.–9 p.m. |
| Thursday | 8 a.m.–9 p.m. |
| Friday | 8 a.m.–9 p.m. |
| Saturday | 9 a.m.–9 p.m. |
| Sunday | 9 a.m.–9 p.m. |
Hours come from the store’s Google Business Profile and can change on holidays — call ahead to confirm.
What Customers Say About Substance Crater Lake Hwy
5 out of 5 from 43 Google reviews · read the reviews on Google
The store holds a perfect 5.0 stars from 43 Google reviews, nearly all praising friendly, well-informed staff who are not pushy.
There are no notable complaints. First-time visitors say staff are good at guiding newcomers through edibles and gummies.
This summary is written by The Weed Street Journal from a sample of public Google reviews. It is not a paid endorsement.
Getting to Substance Crater Lake Hwy in Crater Lake Highway near the airport, north Medford
Substance Crater Lake Hwy is at 3425 Crater Lake Hwy, about 1.1 miles from Rogue Valley International-Medford Airport and 1.7 miles from Rogue Valley Mall and Providence Medford Medical Center. Google lists a wheelchair-accessible entrance and parking lot. Cloud 9 Wellness and The Spot Cannabis Collective are about a mile closer to town.
- Rogue Valley International-Medford Airport — 1.1 mi
- Rogue Valley Mall — 1.7 mi
- Providence Medford Medical Center — 1.7 mi
- Hawthorne Park — 2.5 mi
Substance Crater Lake Hwy Store Details
| Address | 3425 Crater Lake Hwy, Medford, OR 97504 |
|---|---|
| Phone | (541) 317-1814 |
| Website | substancemarket.com |
| Online menu | View menu and order ahead |
| State license | OLCC #050-10174595F3A |
| Medical | Medically endorsed — registered patients can use their medical benefits here |
| Delivery | Home delivery endorsed |
| Accessibility | Wheelchair accessible entrance, Wheelchair accessible parking lot |
| Community | LGBTQ+ friendly |
| Google profile | Verified by the business owner |
Oregon Cannabis Rules for Shopping at Substance Crater Lake Hwy
- Adults 21+ with a valid government photo ID (out-of-state IDs and passports are accepted).
- Daily limits: 2 oz of flower, 10 g of concentrates, 10 g of inhalable products, 16 oz of solid products and 72 fl oz of liquids.
- Retail sales are allowed from 7 a.m. to 10 p.m.; each store sets its own hours inside that window.
- Recreational purchases carry Oregon's 17% state cannabis tax plus up to 3% local tax; OMMP cardholders are exempt.
- Using cannabis in public, in a car or in view of the public is illegal; most hotels and rentals ban it.
See our full guides to dispensaries in Medford and Oregon marijuana laws.
Substance Crater Lake Hwy FAQ
What are Substance Crater Lake Hwy's hours?
Substance at 3425 Crater Lake Hwy in Medford is open 8 a.m. to 9 p.m. Monday to Friday and 9 a.m. to 9 p.m. on weekends, according to its Google Business Profile as of October 2026.
What is the closest dispensary to the Medford airport?
Substance Crater Lake Hwy, about 1.1 miles from Rogue Valley International-Medford Airport.
Does Substance Crater Lake Hwy deliver?
Substance holds an OLCC home-delivery endorsement, and a reviewer mentions ordering online. Ask the store whether it currently delivers to your address. Oregon delivery orders must be placed before 8 p.m. and go to residences in the city.
How many Substance stores are in Medford?
Two: this one on Crater Lake Highway and Substance McAndrews on E McAndrews Road.
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